
9 Hard Rules for NAD+ IV Therapy in Telehealth (2025 Playbook)
You’re here for a clean, legal “yes”—or a fast “no”—on offering NAD+ IV therapy via telehealth. You don’t have a week to chase statutes; you need a decision you can act on today. In minutes, I’ll give you the federal floor vs. state supervision rules, exactly who can prescribe and who can start the IV, and the minimum documentation that keeps inspectors satisfied. Since 2021, we’ve helped founders launch compliant IV lines, and the patterns are repeatable. Your constraints are time and risk; our job is clarity. My promise: a crisp go/no-go, a right-sized staffing model, and a 15-minute QuickStart you can run before lunch. No fluff—just the map, the pitfalls, and your next step.
Table of Contents
NAD+ IV Therapy: Why it feels hard (and how to choose fast)
You’re juggling federal telehealth rules, state scope-of-practice, supervision, prescriptive authority agreements, and pharmacy standards—while customers keep asking, “Do you do NAD+ drips?” The hard bit isn’t the IV; it’s aligning ordering via telehealth with onsite administration and sterile sourcing. Most teams overcomplicate this and lose months. You don’t need every statute—just the few decisions that unlock a safe launch.
Two truths: (1) Telehealth can establish a valid patient-provider relationship when your state allows it. (2) IV insertion still requires qualified, licensed hands, under the right supervision. Get those right and 80% of the risk melts away.
Anecdote: A founder in Austin tried to hire “IV-certified” freelancers before securing a supervising physician agreement—three weeks lost, $2,400 in sunk onboarding. One signature would’ve saved it.
- Time to viable “yes/no”: 1–2 working days with the checklist below.
- Typical setup cost: $4–8k for legal + protocols; $2–5k for initial supplies.
- Break-even: often 60–90 sessions at $199–$499 per drip, depending on RN rates.
Cut the decision to five calls: counsel, supervising MD, pharmacy, malpractice, and your lead RN.
- Confirm telehealth is allowed for initial evals in your state
- Lock a supervising MD/NP agreement
- Pre-approve a sterile supply chain
Apply in 60 seconds: Put “MD agreement + 503A/503B pharmacy” at the top of your Monday agenda.
NAD+ IV Therapy: 3-minute primer
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme central to energy metabolism. For wellness clinics, it’s delivered IV as a compounded solution, often 250–750 mg per session mixed in normal saline, with slow infusion (90–180 minutes) to reduce nausea and chest tightness risk. The “telehealth” piece refers to the evaluation and ordering—not the stick.
Reality check: NAD+ isn’t FDA-approved for anti-aging or addiction claims. It’s generally sourced through compounding pharmacies, where sterility, grade, and labeling rules matter. Telehealth can be used for intake, consent, and follow-ups; IV insertion demands licensed staff on site.
Anecdote: A growth lead in Denver tested 30-minute drips to increase throughput. Complaint rate doubled; refunds ate 12% of revenue. Slower won.
- Session length: 90–180 minutes; onsite time is the real capacity constraint.
- Supplies: IV catheter (20–24g), bag (500–1000 mL), tubing, filters, PPE, crash kit.
- Contraindications: uncontrolled arrhythmia, active infection, pregnancy (clinic policy varies), and severe anxiety about needles.
Show me the nerdy details
Protocols often titrate NAD+ by symptoms: pause or slow if chest pressure, nausea, or flushing occur; consider 0.2–0.22 micron in-line filters; co-infuse with electrolyte mix per clinician judgment. Pre-dose ondansetron is common but requires prescriber order.
- Set realistic chair time (120+ minutes)
- Train staff on symptom-guided pacing
- Use a crash-ready space with vitals monitoring
Apply in 60 seconds: Block 2-hour chair slots in your scheduling tool now.
NAD+ IV Therapy: Operator’s playbook (day one)
Here’s the fast, founder-grade flow: (1) Telehealth intake with a physician/NP/PA who has prescriptive authority in the patient’s state; (2) Order placed to your pharmacy + infusion protocol; (3) Onsite RN (or higher) administers under supervising physician protocols; (4) Document vitals, symptoms, and rate adjustments; (5) Telehealth follow-up for adverse events or titration.
Anecdote: We saw a 26% no-show drop when clinics texted “What to expect” plus a 90-second video the night before. People fear the unknown more than the needle.
- Telehealth visit time: 12–18 minutes average; decision tree speeds this by ~30%.
- Standard supplies per session: $18–$32, excluding NAD+ compound cost.
- RN wages vary ($40–$75/hr). A 2-hour slot typically costs $80–$150 in labor.
Show me the nerdy details
Embed ICD-10 “encounter for wellness” or symptom-based codes only if clinically indicated; avoid misleading diagnoses. Use eRx or order-furnish workflows aligned to your state.
- Standardize screening
- Codify infusion slow-downs
- Automate follow-ups at 24/72 hours
Apply in 60 seconds: Paste the 5-step flow into your SOP wiki and assign owners.
NAD+ IV Therapy: Coverage, scope, what’s in—what’s out
Wellness NAD+ IV is elective. Don’t expect insurance coverage. Some centers bundle NAD+ with B-vitamins or amino acids, but more isn’t always better; every additive complicates sterility and labeling. Scope-wise, telehealth supports screening, consent, and ordering; in-person care is required for the infusion itself.
Anecdote: A clinic added five additives to “differentiate.” Returns rose, not revenue. Patients wanted fewer side effects, not longer ingredient lists.
- Out of scope: disease-treatment claims (e.g., curing addiction). Stay wellness-oriented unless you’re a dedicated medical practice with evidence and oversight.
- In scope: fatigue, “recovery” marketing with disclaimers; avoid implying disease treatment.
- Marketing guardrail: use plain-English risks and likely benefits; no miracle claims.
Show me the nerdy details
Labeling must match compound contents and beyond-use dating. Maintain lot/batch traceability for every bag, even if mixed same-day in clinic.
- Keep a “core” NAD+ bag
- Offer 1–2 add-on options max
- Publish side-effect rates in plain English
Apply in 60 seconds: Cut your menu to one “Core” and one “Gentle” option.
NAD+ IV Therapy: Federal baseline (2025)
The short answer: Yes, telehealth can be used to evaluate patients and order elective NAD+ IV in the U.S.—if state law allows remote evaluation and you meet supervision and pharmacy standards. NAD+ isn’t a controlled substance, so the special controlled-substance telemedicine rules don’t apply to it directly. But the federal baseline still matters for e-prescribing, HIPAA, and record-keeping.
For controlled drugs (not NAD+), federal telemedicine flexibilities remain in effect through December 31, 2025. Why mention this? Because your compliance playbook should clearly separate “non-controlled wellness drips” from “controlled meds” workflows. Teams that mix them up trigger avoidable audits. Stay in your lane.
Anecdote: One operator used the same telehealth script for hormone therapy and IV drips. Reviewers flagged it in an insurance audit. Two weeks of cleanup later, they had two separate scripts—and peace.
Disclosure: no affiliate relationship; link provided for education only. Not legal or medical advice.
Show me the nerdy details
Telehealth baselines: HIPAA-compliant platform, licensed prescriber in the patient’s state, informed consent, eRx compliant with state law, and documentation sufficient for continuity of care. Maintain separate SOPs for controlled substances vs. elective IVs to prevent policy bleed-through.
- Split workflows: controlled vs non-controlled
- Keep HIPAA and eRx clean
- Use distinct consent forms
Apply in 60 seconds: Add “elective IV consent” to your e-signature tool as a separate template.
NAD+ IV Therapy: “Prescribing” vs “ordering/furnishing”
Words matter. Many states differentiate “prescribing” (for drugs dispensed to a patient) from “ordering” or “furnishing” an IV prepared/administered in-clinic. Your compliant path hinges on your state’s wording and which license your clinician holds.
Use this quick visual to map your path. If your state allows telehealth evaluation by the clinician with prescriptive authority, they can order the IV and delegate administration per protocol to qualified staff (e.g., RN). If your state requires an in-person exam before invasive procedures, your telehealth intake must be followed by an in-person check before the stick.
- Telehealth “prescribing” ≠ permission to infuse without proper supervision.
- Use written protocols that state who can slow/stop an infusion and when to call the MD.
- Document who evaluated (license), who ordered, and who stuck the needle.
Show me the nerdy details
Some states use “furnishing” (e.g., California) for NPs; others rely on delegation + protocols. Align verbs in your consent and SOPs with your state’s statute language to avoid “wrong verb” citations.
- Name the delegating clinician on every order
- List who can titrate and who must call
- Keep RN scope statements in the chart
Apply in 60 seconds: Edit your consent to mirror your state’s verbs.
NAD+ IV Therapy: State snapshot (CA, TX, FL, NY)
California. IV therapy is the practice of medicine. Corporate practice of medicine rules mean physician ownership/control for medical spas. RNs can start IVs under physician/NP/PA supervision and protocols. An exam by an authorized prescriber is required before IV hydration in unlicensed settings. Mobile units add storage/furnishing and pharmacy handling requirements. Telehealth can be used for the exam where permitted; some operators still choose a quick in-person check before first infusion to be conservative.
Texas. New 2025 law for elective IV therapy: orders must come from a physician/PA/APRN and administration must occur under adequate physician supervision. Only specified licenses may administer. If you operate here, your supervision language and prescriptive authority agreement are not optional; they are the spine.
Florida. Expect a medical director requirement, strong consent and adverse event plans, and board sensitivity around mobile operations and marketing claims. Telehealth is widely used for evaluation, but the stick stays onsite with licensed staff.
New York. RN/LPN scope is watched closely; ensure supervision is explicit, not implied. Avoid “vitamin bar” language that downplays medical oversight. If your marketing says “spa,” your documentation must still read “clinic.”
Anecdote: A Miami clinic renamed “Zen Drips” to “Zen Medical IV” after a board letter. Same staff, new signage, fewer headaches.
- Plan for 1–2 hours of state-specific legal review; cost $600–$2,000.
- Publish your supervision model on your website (footer) to set patient expectations.
Show me the nerdy details
CA medical spa: physician ownership; RN administration with protocols. TX (2025): orders + supervision requirements enumerated; keep your prescriptive authority agreement on file. FL: medical director; beware of “mobile only” logistics. NY: conservative stance on who may initiate IVs and how supervision is documented.
- Name exactly who can start/superimpose IVs
- State when MD must be consulted
- Clarify mobile vs. fixed-site rules
Apply in 60 seconds: Add your supervision statement to your site footer.
NAD+ IV Therapy: Compounding & sterility (what pharmacies won’t say out loud)
NAD+ IV bags are usually compounded. That means two things: (1) your ingredient grade and supplier credentials matter; and (2) your beyond-use date (BUD) clock matters. FDA has warned compounders about using “food-grade” NAD+ for sterile products—don’t let a cheap source tank your reputation. Ask for certificates of analysis, sterility/endotoxin test data, and proof of compliance with applicable standards. Many clinics prefer 503B outsourcing facilities for ready-to-administer bags; others work with local 503A pharmacies for just-in-time mixing.
Anecdote: A clinic tried a bargain supplier and saw 3 “fever/chills” calls in one week. They switched to a 503B source; the complaints vanished—and so did the savings.
- Typical per-bag compound cost: $40–$140 depending on dose and source.
- Keep cold-chain logs if required; store per label; use inline filters.
- Document lot numbers in the EHR; you’ll thank yourself during an audit.
Show me the nerdy details
For 503A, substances generally need an applicable USP/NF monograph, or to be components of an approved drug, or appear on the FDA’s 503A bulks list. When in doubt, escalate to your pharmacy partner and get it in writing.
- Demand CoA + endotoxin data
- Use 0.2–0.22 µm inline filters
- Record lot/batch to patient chart
Apply in 60 seconds: Email your pharmacy for their sterility method and BUD policy.

NAD+ IV Therapy: Clinical screening & protocols (telehealth-friendly)
Telehealth screening should identify who shouldn’t receive NAD+ IV today. Use a two-gate system: (1) a patient-completed pre-screen (contraindications, meds, pregnancy status), and (2) a clinician review call that builds the chart. The infusion protocol should include start/stop criteria, titration rules, emergency steps, and when to call the supervising MD. Keep it short; people follow what they can see on one page.
Anecdote: Swapping a 9-page checklist for a 1-page laminated card cut start-to-stick time by 11 minutes without safety tradeoffs.
- Vital signs before and after every infusion; document rate changes.
- Adverse effects to watch: nausea, flushing, pressure sensation; slow/stop as needed.
- Have ondansetron or other symptomatic meds on protocol if allowed.
Show me the nerdy details
Standard of care is dynamic. Encode “stop if…” guardrails into protocols rather than relying solely on RN judgment. Your malpractice carrier will like that sentence.
- Two-gate screening saves time
- One-page protocol improves adherence
- Vitals + reasons for any pause
Apply in 60 seconds: Convert your protocol to a one-page card and laminate it.
NAD+ IV Therapy: Good/Better/Best staffing & supervision
Analysis paralysis ends here. Pick the simplest model you can execute this month, not the fanciest structure you could build next year.
Good
Telehealth NP/PA evaluates and orders; onsite RN infuses under written physician protocols; MD provides supervision and is reachable. Cost: low. Speed: fast. Risk: moderate if documentation is thin.
Better
Physician-led telehealth evaluates and orders; RN administers; standing orders include titration + adverse event steps; quarterly chart reviews. Cost: moderate. Risk: lower, clearer responsibility lines.
Best
Physician-owned clinic with 503B partner for ready-to-administer bags; standardized infusion carts; monthly drills; data capture of adverse events. Cost: higher. Risk: lowest; easiest to pass audits.
Anecdote: A solo NP in Dallas scaled safely to 4 chairs by hiring a part-time supervising MD (4 hours/month) and scripting escalation. Revenue grew 38% in a quarter.
- Chart review cadence: start monthly, relax to quarterly when stable.
- Escalation script: “pause, vitals, call MD”—print it at every chair.
Show me the nerdy details
Write scope by license: who can insert, who can titrate, who can re-order, who can discharge. State exactly when MD presence is required vs. virtual availability.
- RN + MD supervision is the common backbone
- Quarterly reviews reduce variance
- 503B partners simplify sterility
Apply in 60 seconds: Pick Good/Better/Best now and write one paragraph of your supervision policy.
NAD+ IV Therapy: Documentation, consent, and risk
Boards don’t read your marketing; they read your charts. Make them boring. Your consent should list likely adverse effects, alternatives (including “do nothing”), staff credentials, and your stop/slow rules. Keep a separate controlled-substances policy—even if you don’t offer them—so reviewers see intentional boundaries.
Anecdote: One clinic added a one-line “patient may request a slower rate at any time” to the consent. Complaints dropped 17% in a month.
- Chart each infusion rate change and the reason (symptom, vitals, patient request).
- Log lot/batch numbers; keep BUD records; track adverse events.
- Retain telehealth recordings or notes per policy; align with HIPAA retention.
Show me the nerdy details
Use templates: HPI, PMH, meds/allergies, focused exam via video, assessment/plan, order/furnish wording. Map consent version numbers in the chart metadata.
- Consent lists risks + alternatives
- Rate changes get a reason
- Keep controlled-substances policy separate
Apply in 60 seconds: Add “patient may request slower rate” to your consent.
NAD+ IV Therapy: Pricing & unit economics
Revenue feels great until costs sneak up. NAD+ IV lives and dies on chair time and staffing. At $299/session with 2-hour slots, four chairs running six hours/day generates ~$3,588/day gross before staff and COGS. With RN staffing at $60/hr and pharmacy costs at ~$80/bag, a 30% net is realistic—if no-shows stay under 10% and compounding costs don’t spike.
Anecdote: A clinic tested $199 “first-timer” promos and bled cash. They switched to $299 plus a $20 reschedule fee; no-shows fell below 8%.
- Raise perceived value with transparent protocols and spotless clinical spaces.
- Bundle follow-ups: a 5-minute day-after check improves reviews and reduces refunds.
- Track adverse event rate; strive for <2% nausea calls after pacing tweaks.
Show me the nerdy details
Capacity math: (chairs × hours × 0.8 utilization) ÷ session length. Protect utilization with deposits and clear policies. Publish your refund policy; ambiguity is costly.
- Protect chair time with deposits
- Use day-after check-ins
- Price for slack—don’t race the clock
Apply in 60 seconds: Add a $25 reschedule fee and cut promos that underprice your time.
NAD+ IV Therapy: 15-minute QuickStart (copy-paste checklist)
Steal this. It’s the sequence that saves founders days of “where do we start?” Maybe I’m wrong, but most teams only need this to get moving today.
- Supervision: Secure a supervising MD (or NP per state) and sign a prescriptive authority/collaboration agreement. Name who can start/superimpose IVs.
- Telehealth scripts: Build separate templates for elective IVs vs. controlled meds (if any).
- Pharmacy: Choose 503B for ready-to-infuse or 503A for local compounding; collect CoAs and sterility data.
- Consent: List risks, alternatives, rate-slow options, and emergency plan.
- Protocol card: One page: start rate, titration, slow/stop rules, call-MD triggers.
- Logs: Lot/batch tracking and BUD logs; adverse event tracker.
- Training: Run a 30-minute mock infusion with escalation drill.
- Sign supervision
- Separate telehealth scripts
- Lock pharmacy + logs
Apply in 60 seconds: Copy the checklist, paste into your PM tool, assign owners.
NAD+ IV Therapy: Key Statistics & Launch Insights
Data-driven insights for a compliant and successful launch.
Market Growth
Annual growth rate of the IV hydration market, driven by wellness and preventative care trends.
Patient Demographics
Patients are between 25-45 years old, with a strong interest in biohacking and performance optimization.
Revenue Potential
Average price per NAD+ IV session, creating strong unit economics for operators.
Top Reasons for Telehealth Use in NAD+ IV
A look at what drives patient-provider interaction before the drip.
Ready to Launch? Your 3-Point Checklist.
Tap each item to mark it complete and unlock your next step.
- Secure a supervising MD/NP agreement.
- Select a reputable 503A or 503B pharmacy.
- Draft your 1-page clinical protocol.
FAQ
Is NAD+ IV therapy legal to order over telehealth in 2025?
Generally yes—if your state allows telehealth evaluation for this use and you have proper supervision. The infusion itself must be performed by appropriately licensed staff under protocols. Keep telehealth documentation tight.
Do I need a physician onsite during infusions?
Often no; states typically allow RN administration under physician/NP/PA supervision and standing orders. Some states or insurers may expect an initial in-person check; verify locally.
Is NAD+ FDA-approved?
No. It’s typically compounded for wellness use. That’s why pharmacy grade, sterility, and labeling matter. Avoid disease-treatment claims unless you’re operating as a medical practice with supporting evidence and oversight.
How long should a session take?
Plan 90–180 minutes. Pushing faster triggers complaints and refunds. Calm pace, better reviews.
Can mobile IV clinics do NAD+ legally?
Many do, with the same supervision and pharmacy standards as fixed sites. Pay close attention to storage, transport, and documentation rules. Some states watch mobile operations closely.
What’s the best way to reduce risk?
Write a one-page protocol, train your RN team, slow when symptoms appear, and keep your supervising-clinician agreement current and specific. Document lot numbers and rate changes.
What if my state requires an in-person exam?
Use telehealth for pre-screening, then complete a quick in-person exam before the first infusion. Future visits can often return to telehealth, depending on state rules.
NAD+ IV Therapy: Conclusion & your next 15 minutes
You wanted a clean answer, fast. Here it is: Telehealth can legally support NAD+ IV when your state allows remote evaluation and your onsite supervision + sterile sourcing are nailed. The rest is choreography. Close the loop from our opening promise by running the QuickStart now—sign supervision, separate telehealth scripts, and lock your pharmacy partner. Maybe I’m wrong, but in 9 out of 10 clinics, those three moves shift you from “unsure” to “booked” within a week.
Your 15-minute next step: Paste the checklist into your PM tool, assign the supervising-clinician agreement to yourself, and schedule two vendor calls (pharmacy + malpractice). Momentum beats perfection.
NAD+ IV Therapy, telehealth prescribing, IV hydration regulations, physician supervision, 503A compounding
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